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BSI jobs board

To post a job advertisement on this page, please contact our Education & Careers Officer, Eolan Healy. Note that this service is free to BSI members and their institutions, as well as our corporate members. There is a small charge of £100 for non-members who wish to advertise. 

Please note, all job vacancies are posted as soon as they are received, and are cleared after the closing date, or after three months, if one is not specified.

For more information about the vacancies, please click on the links below. You may also find it helpful to have a look at our funding opportunities page

Current vacancies

Research Associate in Translational Innate Immunity

University of Glasgow are seeking a highly motivated, academically excellent and proactive Postdoctoral Researcher with a strong background in innate immunity and bioinformatics to join the groups of Dr Mariola Kurowska-Stolarska (Immunologist; principal investigator), Dr Thomas Otto (Bioinformatician) and Dr Stefano Alivernini (clinical researcher) at the Fondazione Policlinico Universitario A. Gemelli - IRCCS  in Rome.

They are a translational myeloid cell lab and have recently delineated the heterogeneity of human synovial tissue macrophages and identified macrophage clusters that may be involved in maintaining human joint free of inflammation. The successful candidate will lead translational research on the role of these different subpopulations of human and mouse synovial tissue macrophages in shaping the synovial tissue microenvironment to identify macrophage-driven mechanisms of joint immune-homeostasis. To achieve this goal, you will use primary cells, FACS-sorted from human synovial biopsies in a unique ex vivo model of human synovium, along with innovative single-cell technologies, tissue spatial transcriptomics and transgenic mouse models that specifically target synovial tissue macrophages.You will hold a position at the University of Glasgow, where you will be embedded in a multicentre Research into Inflammatory Arthritis Centre Versus Arthritis (RACE), which include researchers/clinicians from Glasgow, Oxford, Birmingham, Newcastle and collaborators in Gemelli Hospital in Rome. RACE is a world-leading research centre where discovery research drives development of transformative therapies for arthritis. You will benefit from an intellectually stimulating, vibrant international research/clinical environment and outstanding support facilities.  

You will hold a PhD in Immunology and desirably an MSc in Bioinformatics or equivalent. You will demonstrate capacity to deliver high quality research outputs, illustrated by a strong publication record in high profile journals. Expertise in macrophage biology, single-cell sequencing/epigenetics is essential, and expertise in vivo cre-flox animal models would be desirable.

Institution/Organisation:
University of Glasgow
Application deadline:
Research Assistant (Fixed Term)

The University of Cambridge wishes to appoint a highly motivated Research Assistant to join the group of Dr Rahul Roychoudhuri at the Department of Pathology and assist in the running of a well-funded research lab of approximately 8-10 scientists.
The research will provide a better understanding of how immune function is dysregulated in cancer and inflammatory diseases and aims to inform development of new immune-based therapies for patients with presently intractable disease.
You will be expected to oversee and provide technical support to the laboratory, alongside the group leader, and will be responsible for its day-to-day running. You will be responsible for overall management of the laboratory's animal research programme, which includes managing the laboratory's transgenic mouse colonies using a fully implemented electronic colony management system, liaising with animal technicians, coordinating commercial genotyping of transgenic mice and directly assisting with in vivo experiments. You will closely interact with other researchers within and outside the lab and be involved in the design and implementation of experiments and development of new techniques and research areas. You will also be involved in specific administrative and laboratory management tasks and opportunities will be presented to develop in this role.
Applicants must have a degree in Immunology, Molecular Biology, Cell Biology or a related discipline and experience of mouse immunology, including working with experimental mice, intravenous and intraperitoneal injection, tissue dissection and flow cytometry. Skills in molecular biology and cell biology are also desirable. You will join a young and dynamic group, whose core values include enthusiasm, openness and integrity.

Institution/Organisation:
University of Cambridge
Application deadline:
Research Assistant

The Babraham Institute are looking for a highly motivated Research Assistant to join the laboratory of Dr Sarah Ross. The lab utilises genome- and proteome-wide approaches as well as biochemistry and cellular immunology to discover the molecular mechanisms that control the function of T lymphocytes during physiological and pathological immune responses.  The goal of the lab is to identify factors that may lead to the impairment in immune function associated with ageing, autoimmunity and immunosuppression that can facilitate the growth of cancers. 

This position offers the opportunity to work on an exciting project investigating how oxygen levels modulate the proteome of effector T lymphocytes. The applicant will utilise cutting-edge techniques to quantify changes in protein metabolism in primary cultures of T cells as they adapt to hypoxia. This project aims to generate new understanding of the consequences of oxygen deficiency on T lymphocytes and will provide a foundation of work for future studies. The project will include opportunities to collaborate with experts within the Babraham Institute to develop practical and analytical skills.

The ideal candidate must have a BSc or MSc in biological sciences and an interest in T cell biology. Previous experience in working with cell cultures, flow cytometry and the preparation of samples for mass-spectrometry-based proteomic analyses, or other types of sample preparation that requires careful processing, is highly desirable.

This is a limited term appointment with funding for this post expected to be available for a period of 12 months. 

Institution/Organisation:
The Babraham Institute
Application deadline:
PhD Studentship In Host-Microbiome Interactions

An exciting opportunity to pursue a fully funded PhD studentship within the Host-Pathogen Interactions research group led by Prof Rachel McLoughlin in the School of Biochemistry and Immunology at Trinity College Dublin.

This studentship will investigate how colonisation with an important member of the respiratory microbiome, Staphylococcus aureus, influences development of adaptive immune memory (expansion and activation of resident memory Tcells) and also innate immune memory (modulation of monocyte/macrophage function and metabolic activity), and will determine if this induced memory influences the response to subsequent bacterial and viral infection. Knowledge gained will provided much needed insights into the mechanism by which S. aureus modulates host immunity and facilitate the development of new vaccines and immunomodulatory therapies urgently required to treat pathogenic infections.

The PhD student will have the opportunity to work with state-of-the-art in vivo models of bacterial colonisation using gnotobiotic mice and will acquire technical expertise in immunology, microbiology and metabolism. The student will be encouraged to attend national and international conferences to present their research findings and will have the opportunity to publish in high impact journals. The student will join a wider team of both academic and clinical researchers investigating all aspects of S. aureus immunity.

The studentship will be for 4 years and the successful applicant will be expected to have a first-class honours degree or a high upper second in a biological subject (preferably with a significant immunology component). We are looking for a highly motived candidate with a strong background in cell biology and immunology, ideally in the context of infection. The successful candidate will receive a stipend of €18,000, plus EU fees will be covered for 4 years

Institution/Organisation:
Trinity College Dublin
Application deadline:
Postdoctoral reserach associate in epitope discovery

This post is made available through a Cancer Research UK - Programme Foundation Award. Dr Michele Mishto (Dep. of Immunobiology & CIBCI) is lead investigator of a project entitled “Identification of tumour-specific spliced epitopes to target large cohorts of cancer patients by immunotherapy”. The project is funded by Cancer Research UK (programme Foundation Award) for 6 years, beginning in 2021.

The successful candidate will be expected to lead, under the supervision of Dr Mishto, a programme of research whose principal aim is to identify HLA-I-restricted spliced neoepitopes useful for anti-cancer immunotherapies, characterise their generation and functional antigenicity in melanoma and pancreatic adenocarcinoma patients. Detailed knowledge of applied cellular and molecular biology and immunobiology, biochemistry, mass spectrometry and bioinformatics would be highly advantageous.

The successful candidate will have opportunities to interact with national and international collaborators with a broad expertise, which varies from computational biology to clinics. This post will be located in the Centre for Inflammation Biology and Cancer Immunology (CIBCI) in New Hunt's House on the Guy's Campus, King's College London.

Institution/Organisation:
King's Colleg London
Application deadline:
Postdoctoral research associate

This post is made available through a BRC3 (Infection and Immunity theme) fund. Dr Michele Mishto (Dep. of Immunobiology & CIBCI) is lead investigator of a project entitled “Epitope discovery to develop novel anti-cancer immunotherapies avoiding autoimmune responses”. The successful candidate will be expected to lead, under the supervision of Dr Mishto, a programme of research whose principal aim is to identify and characterise HLA-I restricted epitopes useful for anti-cancer immunotherapies and isolate tool for translational applications. Detailed knowledge of applied cellular and molecular biology and immunobiology would be highly advantageous.

The successful candidate will have opportunities to interact with national and international collaborators with a broad expertise, which varies from computational biology to clinics. This post will be located in the Centre for Inflammation Biology and Cancer Immunology (CIBCI) in New Hunt's House on the Guy's Campus, King's College London

Institution/Organisation:
King's Colleg London
Application deadline:
Postdoctoral Research Assistant

Blizard Institute

Centre for Immunobiology

QMUL are looking to appoint a Postdoctoral Research Assistant in investigating how immunity in older people with asthma changes and how this effects treatment responses - this post is funded by Barts Charity. The position will be based in the lab of Dr Emma Chambers in the Centre for Immunobiology, Blizard Institute at Barts and The London Medical School. The successful candidate should have excellent communication skills, together with the ability to organize and motivate others. They should be able to demonstrate enthusiasm and innovation when faced with challenges and will utilise cross-disciplinary approaches in conducting their research.

Ageing is a global burden and older people are living longer with chronic diseases such as asthma. However, most clinical and research studies on phenotype and control of asthmatic disease to-date have focussed on younger patients, often actively excluding older participants. The aim of the lab is to understand how immunity changes with age and how ageing effects asthma phenotype, severity and treatment responses.

Dr Chambers’ group uses a wide range of immunological and molecular biology techniques including but not limited to; 12-20 colour flow cytometry, isolation of PBMCS, bead based isolation of leukocyte populations, long- and short-term cell culture of primary human cells, cytometric bead array, ELISA, western blots, metabolic analysis of immune cells, confocal microscopy and RNAseq. 

Candidates should be able to demonstrate an ability to learn new techniques and employ their previous experience, which should cover a broad range of immunological and tissue culture techniques. Expertise in immunology, at least 8-12 colour flow cytometry, isolating PBMCs, in vitro cell culture, cytokine assessment by cytometric bead array and/or ELISA is particularly desirable. The successful candidate may be required to assist in other areas of research.

Institution/Organisation:
Queen Mary, University of London
Application deadline:
Postdoctoral Research Associate in Cancer Immunology - Grade 7

Faculty of Health and Life Sciences

Institute of Translational Medicine

A Postdoctoral Research Associate position is available in the Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine. The position is associated with a recently awarded Northwest Cancer Research (NWCR) grant to study the role of soluble isoform of checkpoint receptor CTLA-4 in immune homeostasis, cancer immune regulation and its utility as a biomarker for drug toxicity. The institute is seeking motivated and skilled individual who is prepared to take a leading role in advancing project from both an experimental and intellectual standpoint. You should have a PhD in immunology, molecular biology, cancer biology, biomedicine or a closely related area. You should have broad knowledge of cancer immunology with high level skills in cell culture, molecular assays, flow cytometry, microscopy and immunohistochemistry. Experience in vivo models with a valid Home Office licence would be beneficial. The post is available for 3 years.

Institution/Organisation:
Univerwsity of Liverpool
Application deadline:
Research Associate (Fixed Term)

An opportunity is available for a Postdoctoral Scientist to join the group of Dr. Naomi McGovern at the Division of Immunology, Department of Pathology, Cambridge.

This research seeks to understand the properties of human macrophage and dendritic cell populations in health and disease. They use a combination of techniques, including multi-parameter flow cytometry, CyTOF, single-RNA sequencing, confocal microscopy and cellular functional assays.

The project will involve the processing of human placental samples to isolate and characterise cells of interest, in particular macrophage populations. Your project will be focused on describing the response of placental cells to microbes that can cause congenital infection, such as Listeria monocytogenes and human cytomegalovirus.

They are looking for a motivated and skilled individual who will thrive in a highly collaborative and supportive research group.

Requirements:

  • A PhD in biological sciences awarded by commencement of the position
  • The candidate must be willing to work with human clinical samples.
  • As the research involves clinical samples, the candidate must be able to work flexible hours, including late into the evening and weekends.
  • Prior experience in at least one of the following is required: placental biology, immunology, bioinformatics or flow cytometry.


Fixed-term: The funds for this post are available until 28 February 2022 in the first instance.

Institution/Organisation:
University of Cambridge
Application deadline: