Editors' Choice 2021 Virtual Issue

On behalf of all the editorial team of Clinical & Experimental Immunology, it is our pleasure to present this collection of Editors’ Choice articles from 2021.

A key part of our role as editors is to identify articles with high relevance to translational immunology that are of broad interest to our readers. We believe this collection offers some fine examples of immunological techniques and approaches that provide novel mechanistic or therapeutic insight into the immunopathology of human disease.

All articles in this collection have been published in journal issues from 2021 and are free to view online. We hope you enjoy our collection and we encourage you to spread the word by sharing this free collection of articles with your network. If you’re on Twitter, don’t forget to tag us @CEIjournal!

December | Progressive B cell depletion in human MALT1 deficiency

M. Sonoda, M. Ishimura, K. Eguchi, Y. Yada, N. Lenhartová, A. Shiraishi, T. Tanaka, Y. Sakai, S. Ohga

 

November | A single-center pilot study in Malaysia on the clinical utility of whole-exome sequencing for inborn errors of immunity

A.M. Ripen, C.T. Chear, M.F. Baharin, R. Nallusamy, K.C. Chan, A. Kassim, C.M. Choo, K.J. Wong, S.M. Fong, K.K. Tan, J.P. Nachiappan, K.R. Teo, M.Y. Chiow, M. Hishamshah, H. Ghani, R.R. Muralitharan, S. Bin Mohamad

 

October | The prevalence of anti-neurofascin-155 antibodies in patients with neuromyelitis optica spectrum disorders
S-H. Chang, J. Wang, X. Zhang, N. Zhao, K. Jia, M. Yi, Q-X. Zhang, H. Zhai, X-W Li, C-S Yang, L. Yang, L-J. Zhang

 

September | A1 and A2A adenosine receptors play a protective role to reduce prevalence of autoimmunity following tissue damage
R. Riff, O. Naamani, J. Mazar, Y.S. Haviv, C. Chaimovitz, A. Douvdevani

 

August | Establishing the prevalence of common tissue-specific autoantibodies following severe acute respiratory syndrome coronavirus 2 infection

A.G. Richter, A.M. Shields, A. Karim, D. Birch, S.E. Faustini, L. Steadman, K. Ward, T. Plant, G. Reynolds, T. Veenith, A.F. Cunningham, M.T. Drayson, D.C. Wraith

 

July | Arthritis in systemic lupus erythematosus is characterized by local IL-17A and IL-6 expression in synovial fluid

N. Sippl, F. Faustini, J. Rönnelid, S. Turcinov, K. Chemin, I. Gunnarsson, V. Malmström

 

June | Exhausted T cells in systemic lupus erythematosus patients in long-standing remission
G. Lima, F. Treviño-Tello, Y. Atisha-Fregoso, L. Llorente, H. Fragoso-Loyo, J. Jakez-Ocampo

 

May | Mimicking Behçet’s disease: GM‐CSF gain of function mutation in a family suffering from a Behçet’s disease‐like disorder marked by extreme pathergy

B. Rösler, B. Heinhuis, X. Wang, R. Silvestre, L. A. B. Joosten, M. G. Netea, P. Arts, T. Mantere, D. J. Lefeber, A. Hoischen and F. L. van de Veerdonk

 

April | Possible involvement of regulatory T cell abnormalities and variational usage of TCR repertoire in children with autoimmune neutropenia
S. Goda, S. Hayakawa, S. Karakawa, S. Okada, H. Kawaguchi and M. Kobayashi

 

March | Defective Bcl‐2 expression in memory B cells from common variable immunodeficiency patients
L. del Pino Molina, J. M. Torres Canizales, O. Pernía, R. Rodríguez Pena, I. Ibanez de Caceres and E. López Granados

 

February | Type I interferon regulates cytokine‐delayed neutrophil apoptosis, reactive oxygen species production and chemokine expression
L. Glennon‐Alty, R. J. Moots, S. W. Edwards and H. L. Wright

 

January | Association of the polymorphism of the Toll‐like receptor (TLR)‐3 and TLR‐9 genes with hepatitis C virus‐specific cell‐mediated immunity outcomes among Egyptian health‐care workers
S. F. Abdelwahab, S. Hamdy, A. M. Osman, Z. A. Zakaria, I. Galal, M. Sobhy, M. Hashem, W. R. Allam, M. Abdel‐Samiee, E. Rewisha and I. Waked

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