University of Dundee are recruiting for a highly-motivated and ambitious postdoctoral researcher with a passion for science. Drive, enthusiasm, and an inquisitive mind are essential. The post-holder will be employed on a Medical Research Council (MRC)-funded project that aims to determine the role of transcription factor Nrf2 in tumour-associated macrophages and microglia cells (TAMs) in glioma. They aim to test the hypothesis that Nrf2 activation in TAMs promotes glioma development. This knowledge may open possibilities to suppress the pro-tumour activity of TAMs, and design effective anti-cancer treatments.
Your priorities will include:
- Carry out high quality laboratory-based research, working independently and also contributing to the work and well-being of the group; Uphold the highest levels of research integrity
- Work under the guidance of Professor Albena Dinkova-Kostova, but assume responsibility for leading and driving the project forward
- Undertake a variety of biochemistry, cell biology and molecular biology techniques, including cell-sorting, proteomics, gene expression analysis, western blotting, histology, and immunohistochemistry. In addition, some of the work will involve isolation of microglial cells from transgenic mice
- Continually update knowledge by frequent reading of the literature to keep pace with technical developments and progress on the field
- Use initiative and creativity to problem solve difficulties, learn new techniques and identify new research directions
Who you’re looking for:
- Minimal requirement of a major contribution to at least one publication in a peer-reviewed journal;
- Demonstrable record of publication in good quality journals;
- Scientific background, experience of basic cell and molecular biology techniques is essential, and experience in immunology is advantageous;
- Experience of independently running a project that has demonstrated creativity and initiative.