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B cell differentiation in health and disease

Sheffield Hallam University, Sheffield, UK


The BSI Yorkshire Immunology Group is delighted to host a half-day symposium, 'B cell differentiation in health and disease', at Sheffield Hallam University on Thursday 16 June 2022 from 13:00 to 17:30 BST.

The differentiation of B lymphocytes into antibody-secreting plasma cells is crucial to the humoral immune response to infection and successful vaccination, however, aberrations in these processes can lead to cancers. In this half-day symposium, our invited speakers will describe their latest research on B cell development and the factors that control differentiation and survival of plasma cells in normal and disease states.

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All BSI events will continue to prioritise the health and safety of our members, delegates and staff in light of the COVID-19 pandemic. For more information, please read our COVID-19 guidance here.


13:00 – 13:30 | Welcome and registration

Session 1 | Chairs: Dr Rebecca Leyland and Dr Lynda Partridge

13:30 – 14:15 | Dr Gina Doody (University of Leeds) Uncovering novel aspects of plasma cell biology using in vitro differentiation models 

14:15 – 15:00 | Dr Martin Turner (University of Cambridge) A genetic screen for RNA binding proteins that promote or inhibit the accumulation of plasma cells

15:00 – 15:30 | Tea & coffee

Session 2 | Chairs: Dr Sarah Haywood Small and Dr Helen Marriott 

15:30 – 16:15 | Dr Dinis Calado (Francis Crick Institute) Germinal Center B cells in Physiology and Pathology

16:15 – 17:00 | Dr Sheeba Irshad (King’s College London) B-cell biology in chemotherapy resistant breast cancers

17:00 – 17:30 | Discussion and networking 


Registration is now open. BSI members benefit from free registration at this meeting as well as free or discounted registration at many other BSI events and access to our journals, grants, bursaries and much more. You can sign up to become a member online.

Click here to register online.

BSI member rate Free
Non-member rate £15

Thank you to our sponsors

Bio Rad logo

BSI official journal: call for papers

The British Society for Immunology's official journal Clinical & Experimental Immunology is calling for submissions for a new Special Issue on human B cells. Original research, perspectives and mini-reviews are welcomed on a wide range of topics including human B cell classification, the role of B cells in disease pathology, B cell interactions and features of human B cell subsets.

Your article would accompany a series of invited reviews from top experts in the field, covering a wide variety of topics relating to B cells in the human immune response. Submissions are welcome until 31 July 2022. For more information, visit the call for papers page or contact the Editorial Office at


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