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Discovery to clinical applications of regulatory T cells in autoimmunity and transplantation

Edgbaston Park Hotel, Edgbaston, Birmingham, UK

 

We're pleased to invite you to attend 'Discovery to clinical applications of regulatory T cells in autoimmunity and transplantation', hosted by the BSI West Midlands Immunology Group in conjunction with the University of Birmingham. The event is taking place on Thursday 11 July 2019 at Edgbaston Park Hotel in Birmingham.

The keynote speech will be given by Prof Shimon Sakaguchi, from Osaka University, Japan. The one-day symposium will cover both the function and development of regulatory T cells and how their biology is being exploited in the clinic to combat autoimmune diseases and promote transplantation tolerance.

The event will also provide an opportunity for early career researchers to present their cutting-edge work within the regulatory T cell field.

The BSI's official journals, Immunology and Clinical & Experimental Immunology, will be presenting their new Regulatory T cells Review Series at this meeting. You can find out more here.


Programme

Please find the programme below.  Registration will be open from 08:15

Session 1
Chairs: Dr Kendle Maslowski and Dr David Bending

09:00-9:15 Welcome & introduction to Birmingham cell therapy - Prof David Adams (University of Birmingham)
9:15​-10:00 ​Keynote speaker:  Conversion of effector T cells into Treg cells - Prof Shimon Sakaguchi (Osaka University, Japan)  
10:00-10:30 Optimising the use of Treg to promote transplantation tolerance - Prof Giovanna Lombardi (King’s College London)

10:30-11:00  Coffee/tea

Session 2
Chairs:  Dr Francesca Barone and Dr David Withers

11:00-11:30 Antigen specific immunotherapy of autoimmune diseases - Prof David Wraith (University of Birmingham)
11:30-12:00​ Ultra-low dose IL-2 therapy in autoimmune diabetes - Prof John Todd (University of Oxford)
12:00-12:30 Control of autoimmunity by CTLA-4-dependent Treg function  - Prof Lucy Walker (University College London)
12:30-12:35 Introducing two new Review Series from the BSI Journals “Tregs in Cancer: Where are we now?” and “Regulatory T cells: Exploring Mechanisms for Future Therapies” - Christine Fears (British Society for Immunology). You can find out more and get free access here.

12:35-13:45 Lunch

Session 3
Chairs: Dr Rebecca Drummond and Dr Shishir Shetty

13:45-14:15 Treatment of autoimmune diseases with T regulatory cells in humans – promises and hurdles - Prof Piotr Trzonkowski (Medical University of Gdansk, Poland)
14:15-14:45 Treg therapies in bone marrow transplantation - Prof Matthias Edinger (University of Regensburg, Germany)

Selected abstracts for oral presentation:
14:45-14:55 The 11q13.5 immune disease risk locus contains a distal enhancer required for Treg-mediated suppression of gut inflammation - Dr. Rahul Roychoudhuri (The Babraham Institute, UK)
14:55-15:05 Hepatocytes delete regulatory T cells by enclysis: a CD4+ T cell engulfment process - Dr. Zania Stamataki (University of Birmingham, UK)
15:05-15:15 Parasite cytokines : a structurally novel mimic of TGF-β which potently induces regulatory T cells - Dr. Madeleine White (University of Glasgow, UK)

15:15-15:45  Coffee/tea

Session 4:
Chairs: Dr Zania Stamataki and Dr Paul Collins

15:45​-16:30​ Developing antigen specific Treg therapies in organ transplant & autoimmunity - Prof Qizhi Tang (UCSF, USA)
16:30​-16:45 GMP Treg therapy in autoimmune liver diseases - Dr Ye Htun Oo (University of Birmingham)

16:45 Closing remarks

17:00 - Networking reception


Abstracts

All attendees at the meeting are invited to submit an abstract using our abstract submission form.  Abstracts should be a maximum of 200 words. The abstract submission has now closed.


Registration

Online registration is now open. Early-bird registration deadline: Wednesday 3 July 2019. Registration rates will increase by £5 after the early-bird deadline.

You can join the BSI online - membership provides many benefits to help you progress your career. Undergraduate membership is free. 

BSI members - early-bird fee
BSI member - Full and Early Career* £30
BSI member - Postgraduate** £20
BSI member - Concessionary*** £20
Non-members
Full and Early Career* £65
Postgraduate** £45
Concessionary*** £45
Undergraduate (membership is free) £10

 

BSI members - late booking fee
BSI member - Full and Early Career* £35
BSI member - Postgraduate** £25
BSI member - Concessionary*** £25
Non-members
Full and Early Career* £70
Postgraduate** £50
Concessionary*** £50
Undergraduate (membership is free) £15

 

* Early careers includes scientists employed as post-doctoral researchers, for the first 5 years post graduation.
** Including PhD, Masters
*** Concessionary includes parental leave, career breaks, retired, emeritus retired.


Sponsors

Our thanks to the following sponsors for supporting this event.

 

 

 

If you would like to enquire about sponsorship opportunities, please email Jane Sessenwein.