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Fuelling the immune response: UK immunometabolism meeting 2019

The Assembly Rooms, Newcastle, UK
Thursday, 14 March, 2019 - 09:00 to Friday, 15 March, 2019 - 13:15

 

The British Society for Immunology's new Immunometabolism Affinity Group  is pleased to bring you their inaugural event 'Fuelling the immune response: UK immunometabolism meeting 2019' taking place on 14-15 March 2019 in Newcastle, UK.

If you're attending, why not join the #UKimmunomet19 conversation on Twitter? Follow us @bsicongress.

We are pleased to present the latest Review Series from Clinical & Experimental Immunology, ‘Translating Immunometabolism’. If you’re interested in immunometabolism, follow this link to find out more: www.immunology.org/news/translating-immunometabolism-review-series.


Programme

Thursday 14 March

08:30 - 09:05 Registration and welcome coffee/pastries
09:05 - 09:15 Opening address (from Immunometabolism Affinity Group Committee)

09:15 - 11:00    Session 1

Chaired by Sian Henson (QMUL) & Anna Schurich (Kings College London)

09:15 - 10:00 Keynote address: Doug Green (St. Jude Children’s Research Hospital) - Born different: TORC1 and c-Myc in T cell asymmetric cell division​

10:00 - 10:30 David Finlay (Trinity College Dublin) - Immunometabolism and Natural Killer responses

10:30 - 11:00 Shoba Amarnath (Newcastle University) - Programmed death-1 receptor mediated regulation of FoxP3 in T regulatory cells
 

11:00 - 11:30 Coffee break and meet the exhibitors
 

11:30 - 13:00    Session 2

Chaired by Laura Pallett (UCL) & Daniel Puleston (The Max Planck Institute for Immunology and Epigenetics)

11:30 - 12:00 Linda Sinclair (University of Dundee) - Antigen receptor control of methionine metabolism in T cells

12:00 - 12:15 Short Talk: Lauren Callender (Queen Mary University of London) - Aberrant T cell metabolism in Type 2 Diabetes

12:15 - 12:30 Short Talk: Daniel Puleston (The Max Planck Institute for Immunology and Epigenetics) - Post-Transcriptional control of T cell metabolism

12:30 - 13:00 Ping-Chih Ho (University of Lausanne) - What you eat makes you strong and vulnerable: metabolic targeting intratumoral Tregs for cancer treatment

 

13:00 - 14:00 Lunch

 

14:00 - 15:30    Session 3: PhD Bright Sparks

Chaired by Georgia Perona-Wright (University of Glasgow) & Linda Sinclair (University of Dundee)

14:00-14:15 Claire Gorby (University of Dundee - The effect of IL-10 on the metabolic profile of CD8+ T cells

14:15-14:30 Jack Bibby (King’s College London) - Cholesterol metabolism drives regulatory B cell function

14:30-14:45 Paras Minhas (Stanford University) - Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation

14:45-15:00 Emer Hackett (Trinity College Dublin) - Mycobacterium Tuberculosis limits glycolysis to evade macrophage innate immune responses via modulation of microRNA-21

15:00-15:15 Haiping Wang (University of Lausanne) - CD36-mediated metabolic adaptation guides regulatory T cells in tumors

15:15-15:30 Graham Heieis (University of Glasgow) - Activated Th2 cells are characterised by fatty acid metabolism in vivo

15:30 - 16:00 Coffee break and meet the exhibitors
 

16:00 - 17:30    Session 4: Postdoc Bright Sparks

Chaired by Adam Byrne (Imperial College London) & Frederick Sheedy (Trinity College Dublin)

16:00-16:15 Stefano Angiari (Trinity College Dublin) - Regulation of T cell activation and pathogenicity by dimeric pyruvate kinase M2 (PKM2)

16:15-16:30 Elizabeth Rosser (University College London) - Butyrate-supplementation suppresses arthritis by stabilising the immature phenotype of regulatory B cells

16:30-16:45 Richard Carroll (Royal College of Surgeons, Dublin) - The core clock protein BMAL1 regulates antigen processing in dendritic cells by altering cellular calcium location to control mitochondrial morphology

16:45-17:00 Nathalie Schmidt (University College London) - Rescuing HBV- and HCC-specific T cell responses by modulating cholesterol metabolism

17:00-17:15 Julia Marchingo (University of Dundee) - Myc induction of amino acid transport licenses antigen receptor reprogramming of the T cell proteome

17:15-17:30 Mathilde Raverdeau (Trinity College Dublin) - Impact of different metabolic requirements on the γδ T cells subsets function

 

17:00 - 19:00 Poster sessions with networking reception

19:30 Conference dinner at Assembly Rooms

 

Friday 15 March

09:15 - 11:00 Session 5 title TBC

Chaired by: David Finlay (Trinity College Dublin) & Ping-Chih Ho (University of Lausanne)

09:15 - 09:45 Hal Drakesmith (University of Oxford) - Immunity: the importance of being iron-ic

09:45-10:00 Short Talk: Joe Frost (University of Oxford) - Iron powers adaptive immune responses to immunisations and influenza virus

10:00-10:15 Short Talk: Kirsty Waddington (University College London) - LXR-mediated lipid networks modulate T-cell function and are dysregulated in people with multiple sclerosis

10:15-10:30 Short Talk: Viki Male (University College London) - NK cell function in obesity: a silver lining?

10:30-11:00 Lydia Lynch (Trinity College Dublin / Harvard University) - Fuelling the fire starters
 

10:30 - 11:00 Coffee and meet the exhibitors
 

11:00 - 13:00 Session 6 title TBC

Chaired by: Claudia Kemper (National Institutes of Health, USA / King’s College London) & Claudio Mauro (University of Birmingham) 

11:30-12:00 Claudia Kemper (National Institutes of Health, USA / King’s College London) - Unexpected roles for the Complosme in cell metabolism

12:00-12:15 Short Talk: Georgia Perona-Wright (University of Glasgow) - Helminth products target mTOR/Akt to suppress T cell glycolysis and limit Th2 immunity

12:15-12:30 Short Talk: Michelangelo Certo (University of Birmingham) - SLC5A12-mediated lactate influx into human CD4+ T cells at the inflamed site causes PKM2/Stat3- and fatty acid synthesis-mediated IL17 expression and tissue retention

12:30-13:00 Grahame Hardie (University of Dundee) - AMPK, central regulator of energy metabolism: tumour suppressor or tumour promoter?

13:00 - 13:15 Presentation of prize winners

13:15 Meeting close
 


Abstracts

Delegates are invited to submit abstracts for the opportunity to communicate their work as an oral or poster presentation - there will be lots of presentation slots available. Abstracts should be a maximum of 250 words and should be submitted via our Google Docs form.  The abstract submission deadline has been extended to 18 January 2019.


Registration

Online registration is now open. There is a limited capacity, so please register early to avoid disappointment. BSI membership provides you with many benefits that can help you progress your career. Fees include attendance for both days, refreshments, lunches and the conference dinner.

BSI Member Full & Early Careers

£70

BSI Member Postgraduate member (PhD & Masters)

£40

BSI Member Concessionary member (includes parental leave career breaks, retired, emeritus retired)

£40

Non-Member Full & Early Careers

£110

Non-Member Postgraduate (PhD & Masters)

£80

Non-Member Concessionary member (includes parental leave career breaks, retired, emeritus retired)

£80

Undergraduate (membership is free)

£25

 


 

Sponsors

 

Our thanks go to the following sponsors of this event:

 

Platinum

 

 

Silver 

 

 

 

 

 

Bronze

 

 

 

 

 

 

Stemcell

 

Supporter

 

 

If you would like to enquire about sponsorship opportunities, please email Jane Sessenwein.