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Multi-cellular differentiation-related changes in the immune system during ageing

Academy of Medical Sciences, Portland Place, London, UK
Thursday, 27 September, 2018 - 13:00 to Friday, 28 September, 2018 - 17:00


The British Society for Immunology's Lymphocyte Immunosenescence and Differentiation Group is pleased to bring you 'Multi-cellular differentiation-related changes in the immune system during ageing' taking place on 27-28 September 2018 at the Academy of Medical Sciences in London. 

Both innate and adaptive immunity change during ageing which leads to increased susceptibility to infection and malignancy and a decreased response to vaccination. At the same time altered immune homeostasis may lead to low-grade inflammation and chronic inflammatory conditions. This meeting will highlight changes in leukocyte types during differentiation and/or ageing, how they are integrated, and the impact of intrinsic (cellular-molecular) and extrinsic (physiological/ environmental) factors on immune alterations. We will also discuss strategies for intervention to boost immunity in older adults using evidence from animal and human models.


This meeting will bring together world leaders in cell differentiation and immunosenescence, including eight invited speakers.

Thursday 27 September 2018

13.00–13.50: Registration
13.50–14.00: Welcome

Session 1
14.00–14.30: Senescent B cells: impact on the regulation of protective and autoreactive antibody responses in the elderly​Dr Daniela Frasca , University of Miami, USA            
14.30–15.00: TBCDr Anis Larbi, A* Institute Singapore
15.00–15.15: Short talk selected from abstracts
15.15–15.30: Short talk selected from abstracts

15.30–16.00: Break

Session 2
16.00– 6.30: Aberrant migration of senescent T cells​ - Dr Siân Henson, Queen Mary's University of London, UK     
16.30–17.30: Immunesenescence: causes and corrections​ - Prof Janet Lord, University of Birmingham, UK               

17.30–late: Networking and dinner

Friday 28 September

9.30–10.00: Coffee
10.00–10.10: Welcome

Session 3
10.10– 11.00: The metabolic signature of pro-inflammatory T cellsProf Cornelia Weyand, Stanford University, USA      
11.00–11.30: Immune surveillance of senescent cells: mechanisms and implications for aging​Dr Valery Krizhanovsky, Weizmann Institute of Science, Israel
11.30–11.45: Short talk selected form abstracts
11.45–12.00: TBCDr Claire Wiseman, Milteyi Biotec

12.00 – 14.00: Networking and lunch

Session 4
14.00 – 14.30: TBCProf Mieke Boots, University of Groningen, Netherlands
14.30 – 14.45: Short talk selected from abstracts
14.45 – 15.00: Short talk selected from abstracts
15.00 – 15.15: Short talk selected from abstracts
15.15 – 15.30: Short talk selected from abstracts
15.30 – 16.00: Enhancing immunity during ageing  - Prof Arne Akbar, University College London, UK  

16.00: Closing remarks


There is also the opportunity for eight researchers to present their work chosen from submitted abstracts. Time will be prioritised for interaction and discussion between junior and senior immunologists to facilitate future collaboration aimed at harnessing divergent expertise to study immune cell differentiation and ageing in the UK.   

Delegates are encouraged to submit abstracts on their work for presentations at the meeting. Abstracts of a maximum of 250 words should be submitted to The deadline for abstract submissions has been extended until Friday 31 August 2018. 


Online registration is now open. You can join the BSI online - membership provides many benefits to help you progress your career. Undergraduate membership is free. 


 BSI Members
 BSI Member - Full  £70
 BSI Member - Early Careers *  £70
 BSI Member - Postgraduate (including PhD, Masters)  £40
 BSI Member - Concessionary **  £40
 Non-Member  £150
 Non-Member - Postgraduate (including PhD, Masters) & Concessionary  £70
 Undergraduates  £20

*  Early career members include scientists employed as post-doctoral researchers, for the first 5 years post graduation.
** Concessionary includes Parental leave, Career Breaks, Retired, Emeritus Retired.


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