The COVID-19 National Core Studies (NCS) Immunity programme, in collaboration with Innovate UK and MRC is looking to assess cellular immunity against SARS-CoV- 2. To support this work, KTN is organising a workshop on 'Next generation assays to assess cellular immunity against SARS-CoV-2' on Thursday 15 April, which will include presentations from the NCS Immunity programme.
Humoral immunity, through assessment of antibody specificity and titre, is relatively well advanced and focusses largely on the relative importance of neutralising and non-neutralising antibodies against the SARS-CoV- 2 Spike protein. In contrast, current techniques to measure cellular immune responses are more limited.
This workshop will consider questions on:
- The purpose(s) for which a cellular assay/test needs to be developed – Is it to address whether an individual has been infected in the past and/or the to predict the risk of re-infection/post-vaccine infection, based perhaps on the quality (breath and/or strength) of immune response
- The biomarkers/cellular characteristics that need to be measured and how to measure these, with a particular consideration of T cell characteristics, but other cellular characteristics including, B cell and innate (e.g., NK) cell responses, could be of interest, where appropriately justified
- The format that the assay will need have in relation to the purpose, where the measurement will be made central lab, point of care, low-resource setting, etc) and at what throughput, cost per sample, etc
This workshop is free to attend. Visit the event page to register.