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Translating Immunometabolism Review Series

We are living through a renaissance in metabolism research, which touches many fields of basic research and clinical medicine. Immunometabolism and cancer metabolism have been at the forefront of these studies since the early 2000s. After over a decade of research in the field of immunometabolism, which has deepened our understanding of the basic processes which intertwine metabolic to signalling pathways in the control of adaptive and innate immunity, the time is right to translate these discoveries to the clinical settings.

We are pleased to present the latest Review Series from Clinical & Experimental Immunology, ‘Translating Immunometabolism’.

For this series, editors Sarah Dimeloe and Claudio Mauro have commissioned review articles covering aspects of translational immunometabolism research, touching on inflammation, autoimmunity and cancer.

We hope you enjoy these articles and we encourage you to share this with colleagues online using the hashtag #CEIReview and looping in @CEIjournal

Editorial by Sarah Dimeloe and Claudio Mauro:
Translating immunometabolism: towards curing human diseases by targeting metabolic processes underpinning the immune response
S. Dimeloe and C. Mauro
Clin Exp Immunol.​

T cell metabolism in chronic viral infection
L. J. Pallett, N. Schmidt, and A. Schurich (2019)
Clin Exp Immunol. doi:10.1111/cei.13308

Sculpting tumour microenvironment with immune system: from immunometabolism to immunoediting
Y-R. Yu and P-C. Ho (2019)
Clin Exp Immunol.

Sensing between reactions: how the metabolic microenvironment shapes immunity 
J. Lötscher and M. L. Balmer (2019)
Clin Exp Immunol.

Altered metabolic pathways regulate synovial inflammation in rheumatoid arthritis
U. Fearon, M. M. Hanlon, S. M. Wade and J. M. Fletcher (2019) 
Clin Exp Immunol. doi:10.1111/cei.13228

Immune cell metabolism in autoimmunity​
X. Teng , W. Li  C. Cornaby and L. Morel (2019)
Clin Exp Immunol. doi:10.1111/cei.13277 

Metabolism at the centre of the host-microbe relationship
K. M. Maslowski
Clin Exp Immunol.

Original Research: Underpinning ‘Translating Immunometabolism’ 
Type 2 diabetes is associated with the accumulation of senescent T cells
E. Y. M. Lau,  E. C. Carroll  L. A. Callender,  G. A. Hood,  V. Berryman,  M. Pattrick  S. Finer,  G. A. Hitman, G. L. Ackland and  S. M. Henson
Clin Exp Immunol.

Other Clinical & Experimental Immunology Review Series

Check out our other Review Series on topics such as 'Regulatory T cells: exploring mechanisms for future therapies' and 'Vaccines for Emerging Pathogens: from Research to the Clinic'.



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