Inspired by the advances presented at the Inflammation and Immune Resolution Plenary Session at the British Society for Immunology Congress, December 2017, in this issue of Clinical & Experimental Immunology we present a Review Series on Inflammation and Immune Resolution.
Our selection ranges from an overview of current genetic understanding of the similarities and differences between immune mediated inflammatory diseases (IMIDs); discussion of several biological mechanisms underlying the aberrant activation of myeloid cells in RA, and how myeloid cell relevant anti-inflammatory mediators may contribute to immune resolution; presentation of fascinating evidence for the existence of innate immune memory in stromal cells and how this may exacerbate or restrain inflammatory disease; and a review of how the interleukin (IL)-6 family members IL-6 and IL-27 may drive or regulate inflammation.
Inflammation and immune resolution are two sides of the same coin: the reviews presented in this series aim to equip readers with greater insight into the delicate balance between the two.
Read the series below:
Inflammation and immune resolution
Leonie S. Taams
Genetics of immune-mediated inflammatory diseases
T. David, S. F. Ling and A. Barton
Driving chronicity in rheumatoid arthritis - perpetuating role of myeloid cells
S. Alivernini, B. Tolusso, G. Ferraccioli, E. Gremese, M. Kurowska‐Stolarska and I. B. McInnes
Stroma: the forgotten cells of innate immune memory
T. Crowley, C. D. Buckley and A. R. Clark
IL-27 – a double agent in the IL-6 family
G. W. Jones, D. G. Hill, A. Cardus and S. A. Jones
View more Review Series from Clinical & Experimental Immunology here.