BSI jobs board

Centre for Inflammation Biology and Cancer Immunology (CIBCI), School of Immunology & Microbial Sciences are seeking a highly motivated Postdoctoral Research Associate in Immunology to join Prof Patricia Barral's research team. The successful candidate will investigate the cellular and molecular mechanisms underpinning MAIT cell functions during infection. This role offers the opportunity to apply cutting-edge techniques to address fundamental questions in immunology. You will design and conduct experiments, analyse complex datasets, and contribute to high-impact publications in a collaborative and supportive environment.

This project will take advantage of preclinical model of infection to explore the mechanisms by which MAIT cells protect from disease. As part of the project, you will develop ex vivo and in vivo approaches to identify the cellular and molecular mechanisms controlling MAIT cell functions during infection, and how those can be manipulated for therapy.

The Barral lab has strong expertise in Immunology and aims to understand how immune cells adapt to their environment and how in turn influence health and disease. They foster an inclusive and interdisciplinary culture, providing access to state-of-the-art facilities, training opportunities, and a great network of collaborators. They are committed to support career development and encourage innovative thinking to tackle major challenges in Immunology.

This is a full-time post 35 hours per week, and you will be offered a fixed term contract until 30 Nov 2028.

Salary: £45,031 including London Weighting Allowance

A fully funded four year PhD project at Newcastle University will focus on the development and validation of quantitative assays for nephritic factors in complement mediated kidney disease.

Based within the National Renal Complement Therapeutics Centre and Complement Therapeutic Research Group, this project offers a bench to bedside research environment integrating clinical care, advanced genetic testing and translational science. You will be supervised by David Kavanagh, Neil Sheerin and Kevin Marchbank.

The project will involve developing assays to detect and quantify autoantibodies known as nephritic factors, which drive excessive complement activation and kidney damage. You will use a range of immunological and protein based techniques, working with international collaborators, and apply these assays to patient samples to better understand disease activity and outcomes.

The assays developed are expected to be adopted into clinical care and support the design of future clinical trials for emerging treatments in complement mediated disease.

You will gain experience in laboratory immunology and protein biology techniques within a translational research setting, with insight into the link between laboratory discovery and clinical application.

Informal enquiries can be made to David Kavanagh (David.Kavanagh@ncl.ac.uk) or Kevin Marchbank (Kevin.Marchbank@ncl.ac.uk).

Funding: UKRI stipend (indicative £21,805 per year) plus tuition fees and research costs for four years (UK students).

A fully funded four year PhD project at Newcastle University will explore the mechanisms driving thrombotic microangiopathy associated with MMACHC deficiency and hyperactive C3, with a focus on atypical haemolytic uraemic syndrome.

Based within the National Renal Complement Therapeutics Centre and Complement Therapeutic Research Group, this project offers a bench to bedside research environment integrating clinical care, advanced genetic testing and translational science. You will be supervised by Kevin Marchbank and David Kavanagh.

The project will involve analysing UK patient cases and investigating non complement mediated aHUS using translational models. You will apply biochemical, histological and molecular approaches, alongside proteomic and RNA sequencing techniques, to identify and target disease pathways, with the aim of accelerating clinical translation.

You will join a multidisciplinary team of clinicians and researchers working on rare kidney diseases and gain training across a wide range of pre clinical techniques. The role also includes opportunities to contribute to publications and public engagement activities with patient groups and charities.

Informal enquiries can be made to David Kavanagh (David.Kavanagh@ncl.ac.uk) or Kevin Marchbank (Kevin.Marchbank@ncl.ac.uk).

Funding: UKRI stipend (indicative £21,805 per year) plus tuition fees and research costs for four years (UK students).

The Osaka University Immunology Frontier Research Center (IFReC) is recruiting post-doctoral researchers for its Advanced Postdoc Program. This program offers three-year employment and funding (3 million yen per year) for original research to promising young researchers. Selected applicants have access to continually upgraded state-of-the-art facilities at IFReC for their research, including equipment for single-cell analysis. Furthermore, selected applicants can expect their research careers to develop immensely through invaluable guidance from their supervisor among IFReC’s many distinguished Principal Investigators as well as through collaborative research with them. We look forward to receiving applications from ambitious young researchers. 

Annual Salary: JPY 5.7M - 7.7 M

Research Grant: JPY 3M per year

Period of employment: 1 year from the date of hire (renewable up to 3 years)