The Gwyer Findlay lab investigates how neutrophils affect T cell phenotype. Their work sits at the interface of immunology and inflammation biology and they use a variety of methods in their studies – immunology, molecular biology, computational biology and imaging.
In this project they are aiming to understand how neutrophils alter T cell cytokine production. They have previously shown that when neutrophils release antimicrobial peptides, they enter nearby T cells and profoundly alter T cell cytokine production. In particular, they affect the production of the IL-17 family of cytokines. In this project they will work out how this occurs. Through culture of mouse and human T cells, flow cytometry, RNA and ATAC sequencing and imaging, they will examine the signalling pathways induced by neutrophil peptides and how they lead to differential IL-17 production.
You will hold a PhD in immunology, biology, or a related discipline. Highly organised and driven, you will demonstrate initiative and problem-solving skills. You will have experience in and knowledge of T cell immunology, cell culture, and flow cytometry.
Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon completion of PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.
What they can offer you
- a world-class research environment
- access to mentoring, career development and networking across the University and beyond
- a personalised training and development plan including external training courses and attendance at conferences
- a friendly, supportive lab environment