BSI jobs board

Oxford University are seeking a highly-motivated Postdoctoral Researcher for a new post recently funded under a joint call from UKRI and the Japanese Society for the Promotion of Science (JSPS). This project focuses on using structural and functional information from HIV-2 as a novel approach to HIV-1 vaccine design. Reporting to Professor Sarah Rowland-Jones, the post-holder will be a member of a research group in the Nuffield department of Medicine in Oxford, with responsibility for carrying out research as part of this joint project with collaborators in the University of Hokkaido in Japan. Our group will study cellular immune responses to HIV-2 in the UK HIV-2 cohort, with a particular focus on cytotoxic T lymphocyte (CTL) responses to HIV-2 proteins, whilst our Japanese colleagues will focus on structural analysis of HIV-2 proteins and T-cell receptors of HIV-2-specific T-cells.
The post holder will undertake experiments and will write up their results to complete the project. You will manage own academic research and administrative activities.  You will also present results in laboratory meetings to both the Oxford group and our Japanese collaborators, as well as at national/international conferences, and prepare data for publication. In addition, the post holder will provide guidance to less experienced members of the research group, including PhD, visiting and undergraduate project students. 
You must hold or be close to completion of a relevant PhD/DPhil and have an excellent track record in academic achievement, including publication record.  You will have the ability to manage own academic research and contribute ideas for new research projects and research income generation.  Excellent communications skills and the ability to work well with a team are also essential.
This full-time position is fixed term for 36 months.

This position is for a Post-doctoral Research Associate to join the Inflammation Biology Group at the Centre for Inflammation Biology and Cancer Immunology (CIBCI). The project aims to dissect the signalling pathways that regulate the functions of tissue-resident mononuclear phagocytes, including macrophages and dendritic cells (Baratin et al. Immunity 2015 42(4):627-39; Dalod et al. EMBO J 2014 33(10):1104-16). The project will employ lineage-specific gene targeting in mice combined with emerging technologies such as single-cell genomics and mass cytometry. In depth knowledge of immunology and experience with multi-colour flow cytometry analysis of mouse tissues are essential. Background knowledge of mononuclear phagocyte biology and signalling pathways would be an advantage. Working knowledge of systems biology approaches, genomics and mass cytometry would also be an advantage but is not essential.
This post will be offered on a fixed-term contract for 24 months.

The Laboratory of Immunity and Metabolism, Division of Infection and Immunity based in the School of Medicine at Cardiff University, is seeking a highly motivated and outstanding individual to join our Faculty as part of a new hub of Systems Modellers in the cross-disciplinary science and medicine programme of the Laboratory of Infection and Immunity.
 
Candidates must have PhD or equivalent as well as significant experience and a proven record of outstanding computational accomplishments in the research areas of numerical modelling, complex and dynamical systems. A background in at least one or more fields of mathematics, physics, engineering or statistics would be required. A strong interest in control and dynamical systems theory would be an advantage. While knowledge of biological systems is desirable it is not essential. The successful candidate will initiate and maintain an original, competitive and independently funded research of international calibre, aligned with key strategic objectives of the Laboratory of Immunity and Metabolism. Collegial, team science interactions will be an important element in success.

This is a full time post (35 hours per week), open ended and availability immediately.

The Leiden University Medical Center (LUMC) are looking for a motivated and ambitious postdoctoral researcher to work on a project that aims to analyse the immune system of populations that reside in different geographical areas and respond to vaccines in a very different way. The work aims to answer the question how regulatory immune responses contribute to the poor efficacy of vaccines in rural areas of low to middle income countries. This research will contribute to the development of novel effective vaccines where they are needed most. 

For this project, samples are available from several field studies conducted in rural areas of low to middle income countries where exposure to micro- and macro-organisms is high. In addition, samples are available from series of unique controlled human infection studies conducted at the LUMC and other centers in Europe. You will work together with a team of international collaborators to use high-dimensional CyTOF, flow cytometry and specialized data analysis methods to gain new insights in immunological profiles associated with immune regulation and vaccine responses. You will be expected to design functional experiments to understand mechanisms underlying poor vaccine efficacy in rural areas of low to middle income countries. The position is for two years and based in the Leiden Immuno-parasitology Group (LIPG) within the department of Parasitology.