The BSI Inflammation Affinity Group is delighted to present “Innate immunity & inflammation: UK inflammation 2025 meeting”, a premier event showcasing the latest research in inflammatory mechanisms. This two-day event will bring together leading experts to explore cutting-edge developments, from the role of innate immune cells to inflammasome signalling and highlight recent advances in basic cellular biology with translational impact on clinical approaches.
With a strong focus on fostering discussions and collaborations, the programme will feature outstanding speakers from across the UK, Europe, and beyond. There will also be dedicated opportunities for early career researchers to present their work through oral and poster presentations.
The BSI Inflammation Affinity Group looks forward to welcoming you to Holiday Inn Manchester City Centre on 11 to 12 September 2025 for an exciting and insightful meeting.
For updates, follow us on X and Bluesky and use the hashtag #BSIInflammation25.
Programme
DAY 1: Inflammasome-centric
09:00 | Registration and refreshments
10:00 | Opening address
Session 1: Inflammasome in disease
Chairs: Dr Samuel Lara Reyna (University of Leeds, UK) and Flora Bertwistle (Brighton & Sussex Medical School, UK)
10:15 | KEYNOTE SPEAKER: Professor Pablo Pelegrín (Biomedical Research Institute of Murcia (IMIB-Arrixaca), Spain)
Translating inflammasomes: a journey from bench to bedside
11:00 | Selected short talk: Dr Thea Mawhinney (Queen's University Belfast, UK)
Ferritin: a novel DAMP driving inflammation in acute respiratory distress syndrome (ARDS)
11:15 | Selected short talk: Qi Su (University of Oxford, UK)
Chronic inflammation disarms inflammasome-stimulating particulate adjuvants
11:30 | Selected short talk: Erin Getty (Trinity College Dublin, Ireland)
Functional analysis of hidradenitis suppurative inflammasome protein mutations
11:45 | Invited speaker: Dr Stefan Roth (LMU Munich, Germany)
Neutrophil-derived cell-free DNA induces early recurrent vascular events after stroke
12:15 | Lunch, posters and meet the exhibitors
Session 2: Inflammasome signalling mechanisms
Chairs: Dr Kendle Maslowski (University of Glasgow, UK) and Erin Getty (Trinity College Dublin, Ireland)
13:30 | Invited speaker: Professor David Brough (University of Manchester, UK)
Regulation of the NLRP3 inflammasome
14:00 | Selected short talk: Dr Nathan Leborgne (University of York, UK)
Activation of the non-canonical inflammasome in human NK cells drives human-specific anti-microbial response
14:15 | Selected short talk: Dr Weidong Jing (University of Cambridge, UK)
Synergistic activation of NLRC4 and NLRP3 inflammasomes in autoinflammation driven by NLRC4 gain-of-function mutations
14:30 | Selected short talk: Dr Tara Gleeson (University of Manchester, UK)
Cell volume changes: An underexplored component of the innate immune response?
14:45 | Invited speaker: Dr Rebecca Coll (Queen's University Belfast, UK)
Turning up the heat on NLRP3: novel mechanisms of inflammasome regulation
15:15 | Sponsor talk: Tom Burley, (Alamar Biosciences, UK Regional Business Manager)
Comprehensive immune profiling with NULISA – an automated ultra-sensitive proteomics platform for biofluids
15:25 | Refreshment break and meet the exhibitors
Session 3: Innate immune mechanisms
Chairs: Dr Jack Green (University of Manchester, UK) and Ada Liebenau (University of Oxford, UK)
16:00 | Invited speaker: Professor Clare Bryant (University of Cambridge, UK)
New mechanisms in toll-like receptor signalling
16:30 | Selected short talk: Marcin Krzysztof Maniak (The University of Edinburgh, UK)
Defining the role of interstitial fluid pressure in shaping macrophage functions in inflammation
16:45 | Selected short talk: Jessica Morris (Lancaster University, UK)
Replication stress is detected as stress-associated molecular pattern by IFI16 in cancer cells
17:00 | Selected short talk: Dr Victor Tapia (University of Manchester, UK)
25-Hydroxycholesterol promotes red blood cell phagocytosis and recovery after intracerebral haemorrhage
17:15 | Invited speaker: Dr Katia Cosentino (UNIMORE – University of Modena and Reggio Emilia, Italy)
Membrane pores in inflammatory cell death
17:45 | Poster session with networking reception
DAY 2: Innate immunity-centric
Session 4: Cell death in innate immunity
Chairs: Dr Rebecca Coll (Queen's University Belfast, UK) and Yashila Dewan (Canterbury Christ Church University, UK)
09:00 | Invited speaker: Dr Kendle Maslowski (University of Glasgow, UK)
Salmonella camping out: The role of extracellular versus intracellular bugs in Salmonella cancer therapy
09:30 | Selected short talk: Abraham Noé Rosas Escareño (Max Planck Institute Biophysik, Germany)
Switching death: Optogenetic dissection of inflammasome-dependent pyroptotic signaling
09:45 | Selected short talk: Dr Davey Kneafsey (University of York, UK)
Caspase-4 substrates control ferroptosis execution
10:00 | Selected short talk: Alexander Redmond (University of Oxford, UK)
The soluble isoform of the type I interferon receptor is a negative regulator of antiviral gene expression
10:15 | Invited speaker: Dr Venizelos Papayannopoulos (The Francis Crick Institute, UK)
Mechanisms of NET stability and degradation
10:45 | Refreshment break and meet the exhibitors
Session 5: Innate immunity driving disease
Chairs: Dr Dave Boucher (University of York, UK) and Marissa DiLucca (University of Cambridge, UK)
11:15 | Invited speaker: Professor Sinisa Savic (University of Leeds, UK)
The role of the innate in immunity in haematoinflammatory disorders
11:45 | Selected short talk: Natasha Carmichael (University of Manchester, UK)
Longitudinal IL-6 is predictive of post stroke cognitive decline
12:00 | Invited speaker: Dr Jelena Bezbradica Mirkovic (University of Oxford, UK)
Mapping the tissue biology of inflammasome activation in sterile inflammation
12:30 | Selected short talk: Dr Ryan James Hodgetts (University of Manchester, UK)
Immune biomarkers to improve early lung cancer detection at community lung health checks
12:45 | KEYNOTE SPEAKER: Professor Christopher Buckley (University of Oxford, UK)
Fibroblasts: Master regulators of inflammation
13:30 | Prize presentations and closing remarks
13:45 | Lunch
14:30 | Close
Registration
Registration is open, book your place here.
BSI members benefit from reduced registration fees at this meeting and other BSI events, as well as free access to our journals, grants, career development activities and much more. You can sign up to become a member online. For current BSI members, your reduced fee will be applied automatically if you are logged in to your account. All fees include VAT.
If you require accommodation, please click here to book a bedroom at the Holiday Inn Manchester City Centre hotel. Please note that bedrooms are limited and available on a first-come, first-served basis, so we recommend booking early to avoid disappointment.
Early Bird
The deadline for Early Bird registration is 23:59 on Wednesday 27 August.
| BSI member | Non-member | |
|---|---|---|
| Full | £88 | £145 |
| Early Career/Clinician in training (read the criteria) | £88 | £145 |
| Postgraduate (anyone studying a PhD or Masters) | £57 | £99* |
| Senior (Retired) (read the criteria) | £57 | £99* |
| Discounted membership/rate (read the criteria) | £57* | £99* |
| Undergraduate (membership is free) | £26 | n/a |
Late registration
| BSI member | Non-member | |
|---|---|---|
| Full | £113 | £170 |
| Early Career/Clinician in training (read the criteria) | £113 | £170 |
| Postgraduate (anyone studying a PhD or Masters) | £82 | £124* |
| Senior (Retired) (read the criteria) | £82 | £124* |
| Discounted membership/rate (read the criteria) | £82* | £124* |
| Undergraduate (membership is free) | £51 | n/a |
*If this fee applies to you, please contact meetings@immunology.org for a discount code prior to registering
BSI grants to support your attendance at this event
As part of our career development package, we have two grants available to BSI members to support your attendance at this event.
- BSI Regional & Affinity Group Conference Grants: BSI members can apply for up to £100 to contribute towards their travel costs in attending this conference. In this scheme, we have 10 grants available for this conference and they will be allocated on a first come, first served basis to eligible BSI members. Deadline: Thursday 21 August 2025. Find out more and apply.
- BSI Regional & Affinity Group Carers' Grants: BSI members can apply for up to £100 to contribute towards extra care arrangements costs they incur during the conference, for example, childcare costs, or for additional care for the applicant themselves. Deadline: Thursday
21 August 2025. Find out more and apply.
Abstract Submission
Abstract submission is closed.
Sponsorship
Thank you to our sponsors who are supporting this event.
Principal sponsor
Sponsors
If you are interested in sponsoring this event, please contact our Events & Corporate Engagement Manager, Becky Dempsey, at b.dempsey@immunology.org