In celebration of World Cancer Day 2023 the British Society for Immunology is pleased to collect together recent articles from our official journals Clinical & Experimental Immunology, Discovery Immunology and Immunotherapy Advances which highlight cutting-edge research into cancer immunology and immunotherapy.
Knowledge of the mechanisms by which the immune system interacts with cancer as it develops is increasing rapidly. From this field, cancer immunotherapy has emerged as one of the most exciting and promising approaches to treating cancer. These developments have translated into medical breakthroughs for many cancer patients, although the high prevalence of non-responders and adverse reactions reveals that there are still significant challenges to overcome.
This collection features research and reviews on key topics in the field topics such as CAR-T cell therapies, antibody biomarkers, adverse events and new drug mechanisms. All articles are free to read online.
We hope you enjoy reading this collection of articles and we encourage you to share this using the hashtag #WorldCancerDay and looping in @CEIjournal, @discovimmunol and @IMTadvances.
Clinical & Experimental Immunology, Immunotherapy Advances and Discovery Immunology are the official journals of the British Society for Immunology. Profits derived from the sale of the journals are invested back into the BSI, providing major financial support for the Society's activities. Support the journals and the Society by considering the journals for your next submission!

Clinical & Experimental Immunology
Research article
Immune checkpoint inhibitors and cellular treatment for lymphoma immunotherapy
F Li, Y Chen, M Pang, P Yang, H Jing
Review
Antibodies as biomarkers for cancer risk: a systematic review
Maria J Monroy-Iglesias, Silvia Crescioli, Kerri Beckmann, Nga Le, Sophia N Karagiannis, Mieke Van Hemelrijck, Aida Santaolalla
Review
Immunotherapeutic targeting of activating natural killer cell receptors and their ligands in cancer
Matthias Peipp, Katja Klausz, Ammelie Svea Boje, Tobias Zeller, Stefan Zielonka, Christian Kellner
Research article
Panobinostat enhances NK cell cytotoxicity in soft tissue sarcoma
Xiuxia Lu, Mengmeng Liu, Jing Yang, Yi Que, Xing Zhang
Review
Does CCL19 act as a double-edged sword in cancer development?
Arezoo Gowhari Shabgah, Zaid Mahdi Jaber Al-Obaidi, Heshu Sulaiman Rahman, Walid Kamal Abdelbasset, Wanich Suksatan, Dmitry O Bokov, Lakshmi Thangavelu, Abduladheem Turki Jalil, Farhad Jadidi-Niaragh, Hamed Mohammadi, Kazem Mashayekhi, Jamshid Gholizadeh Navashenaq

Discovery Immunology
Review
What do cancer-specific T cells ‘see’?
Sabaria Shah, Abdullah Al-Omari, Katherine W Cook, Samantha J Paston, Lindy G Durrant, Victoria A Brentville
Research article
NKG2D signaling regulates IL-17A-producing γδT cells in mice to promote cancer progression
Sophie Curio, Sarah C Edwards, Toshiyasu Suzuki, Jenny McGovern, Chiara Triulzi, Nagisa Yoshida, Gustav Jonsson, Teresa Glauner, Damiano Rami, Robert Wiesheu, Anna Kilbey, Rachel Violet Purcell, Seth B Coffelt, Nadia Guerra

Immunotherapy Advances
Review
Guilherme Ferreira de Britto Evangelista, Amanda Braga Figueiredo, Milton José de Barros e Silva, Kenneth J Gollob
Research article
Stephanie Schwartz, Nidhi Patel, Tyler Longmire, Pushpa Jayaraman, Xiaomo Jiang, Hongbo Lu, Lisa Baker, Janelle Velez, Radha Ramesh, Anne-Sophie Wavreille, Melanie Verneret, Hong Fan, Tiancen Hu, Fangmin Xu, John Taraszka, Marc Pelletier, Joy Miyashiro, Mikael Rinne, Glenn Dranoff, Catherine Sabatos-Peyton, Viviana Cremasco
Review
An overview of CAR T-cell clinical trial activity to 2021
Antonella Adami & John Maher
Review
A glutamine ‘tug-of-war’: targets to manipulate glutamine metabolism for cancer immunotherapy
Laura J Pallett, Sarah Dimeloe, Linda V Sinclair, Adam J Byrne, Anna Schurich
Research article
Type 2 immunity is maintained during cancer-associated adipose tissue wasting
Patrick J Lenehan, Assunta Cirella, Amiko M Uchida, Stephanie J Crowley, Tatyana Sharova, Genevieve Boland, Michael Dougan, Stephanie K Dougan & Max Heckler
Clinical & Experimental Immunology, Immunotherapy Advances and Discovery Immunology are the official journals of the British Society for Immunology. Profits derived from the sale of the journals are invested back into the BSI, providing major financial support for the Society's activities.
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